Manu Lopus Selected Research

Colchicine

2/2012

In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).

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Manu Lopus Research Topics

Disease

30	Neoplasms (Cancer) 04/2024 - 04/2006
9	Breast Neoplasms (Breast Cancer) 02/2024 - 04/2006
4	Triple Negative Breast Neoplasms 04/2024 - 12/2019
2	Alzheimer Disease (Alzheimer's Disease) 01/2022 - 01/2010
1	Adenocarcinoma 04/2024
1	Colorectal Neoplasms (Colorectal Cancer) 04/2024
1	Infections 02/2024
1	Respiratory Tract Infections (Respiratory Tract Infection) 02/2024
1	Disease Progression 06/2023
1	Parkinson Disease (Parkinson's Disease) 01/2022
1	Melanoma (Melanoma, Malignant) 09/2021
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 03/2015
1	Adenocarcinoma of Lung 03/2015
1	Lymphoma (Lymphomas) 07/2011
1	Cognitive Dysfunction 01/2010
1	T-Cell Lymphoma (Lymphoma, T Cell) 06/2006
1	Ovarian Neoplasms (Ovarian Cancer) 06/2006

Drug/Important Bio-Agent (IBA)

13	TubulinIBA 02/2024 - 04/2006
13	Noscapine (Narcotine)IBA 11/2020 - 04/2006
5	GoldIBA 04/2024 - 10/2019
3	PhytochemicalsIBA 04/2024 - 01/2023
3	Taxoids (Taxanes)IBA 07/2011 - 04/2006
2	SilverIBA 02/2024 - 01/2022
2	lissamine rhodamine B (sulforhodamine B)IBA 10/2020 - 02/2019
2	Antineoplastic Agents (Antineoplastics)IBA 01/2018 - 03/2015
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2017 - 06/2006
2	ixabepilone (BMS 247550)FDA Link 01/2017 - 11/2015
2	eribulin FDA Link 01/2017 - 10/2015
2	Maytansine (Maitansine)IBA 08/2011 - 10/2010
2	Antimitotic AgentsIBA 07/2011 - 06/2006
1	CaspasesIBA 04/2024
1	Anti-Bacterial Agents (Antibiotics)IBA 02/2024
1	Carbon Nanotubes (Carbon Nanotube)IBA 01/2024
1	Photosensitizing Agents (Photosensitizers)IBA 01/2024
1	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2024
1	Therapeutic UsesIBA 06/2023
1	EnzymesIBA 06/2023
1	Cathepsin BIBA 06/2023
1	Proteins (Proteins, Gene)FDA Link 01/2022
1	talimogene laherparepvecIBA 09/2021
1	N-propargylIBA 10/2020
1	isoquinolineIBA 02/2019
1	triphalaIBA 02/2018
1	gamma-sitosterol (beta-sitosterol)IBA 01/2018
1	Phytosterols (Plant Sterols)IBA 01/2018
1	pyridineIBA 01/2017
1	1,2,3,4-tetrahydroisoquinolineIBA 01/2017
1	Designer DrugsIBA 01/2017
1	Ado-Trastuzumab EmtansineIBA 01/2017
1	epothilone B (EPO906)IBA 11/2015
1	AnthracyclinesIBA 10/2015
1	taxaneIBA 10/2015
1	OpiumIBA 01/2015
1	tasidotinIBA 10/2013
1	cemadotin (LU 103793)IBA 10/2013
1	DNA (Deoxyribonucleic Acid)IBA 01/2013
1	Colchicine FDA LinkGeneric 02/2012
1	Folic Acid (Vitamin M)FDA LinkGeneric 02/2012
1	Podophyllotoxin (Condylox)FDA LinkGeneric 02/2012
1	AntibodiesIBA 10/2010
1	Peptides (Polypeptides)IBA 01/2010
1	alanylprolineIBA 01/2010
1	9-nitronoscapineIBA 06/2006
1	Vinblastine (Vinblastine Sulfate)FDA Link 06/2006
1	Teniposide (VM 26)FDA Link 06/2006
1	sanguinarineIBA 05/2006
1	EM015IBA 04/2006
1	furanIBA 04/2006

Therapy/Procedure

4	Therapeutics 06/2023 - 08/2011
3	Drug Therapy (Chemotherapy) 01/2017 - 07/2011
1	Photothermal Therapy 01/2024
1	Ayurvedic Medicine (Siddha Medicine) 01/2023